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Department of Mechanical Engineering

Prof. Ching-Lung Tai

Ching-Lung Tai  

Research areas: Biomechanics; Medical Engineering; Experimental mechanics; Orthopaedics
Laboratory: Biomedical Experimental Mechanics Lab
Tel: +886-3-2118800 ext. 5342 (Office), 3604 (Lab)

- Ph. D., Medical Engineering, Chung Yuan Christian University, Taiwan
- M.S., Materials Science and Engineering, National Cheng Kung University, Taiwan
- B.S., Materials Science and Engineering, National Tsing Hua University, Taiwan

- Professor, Graduate Institute of Medical Mechatronics, Chang Gung University (2017, 8 ~ present)
- Associate Professor, Graduate Institute of Medical Mechatronics, Chang Gung University (2011, 8 ~ 2017, 7)
- Assistant Professor, Graduate Institute of Medical Mechatronics, Chang Gung University (2006, 8 ~ 2011, 7)
- Researcher, Department of Orthopedics, Chang Gung Memorial Hospital (2003, 10 ~ 2006, 8)
- Research Associate, Department of Orthopedics, Chang Gung Memorial Hospital (1994, 1 ~ 2003, 10)
- Engineer, Material Science Center, Chung-Shan Institute of Science and Technology (1985, 6 ~ 1994, 1)

Selected Publications: (Complete List)
  1. Wu CC, Tai CL “Anterior transfer of tibialis posterior tendon for treating drop foot: Technique of enforcing tendon implantation to improve success rate” Acta Orthop Belg, In Press, 2014.
  2. Tai CL, Liao PI, Peng WY “Biomechanical investigation of the retrograde intramedullary nail fixation for distal femoral periprosthetic fracture after total knee arthroplasty” Applied Mechanics and Materials, 684:389-394, doi:10.4028/www.scientific.net/AMM.684.389, Oct, 2014
  3. Tai CL, Chen YL, Chen SY “Temperature Control of Bone Cement for Enhancing Applicability and Safety in Vertebroplasty”, Applied Mechanics and Materials, 684:395-399, doi:10.4028/www.scientific.net/AMM.684.395. Oct, 2014
  4. Tai CL, Chen YC, Hsieh PH “The effects of necrotic lesion size and orientation of the femoral component on stress alterations in the proximal femur in hip resurfacing - a finite element simulation” BMC Musculoskelet Disord, 15(1):262, doi:10.1186/1471-2474-15-262, Aug, 2014.
  5. Chang YH, Tai CL, Hsu HY, Hsieh PH, Lee MS, Ueng SW “Liquid antibiotics in bone cement: an effective way to improve the efficiency of antibiotic release in antibiotic loaded bone cement” Bone Joint Res, 3(8):246-51, Aug, 2014
  6. Tai CL, Chen LH, Lee DM, Liu MY, Lai PL “Biomechanical comparison of different combinations of hook and screw in one spine motion unit - an experiment in porcine model” BMC Musculoskelet Disord, 15(1):197, doi:10.1186/1471-2474-15-197, June, 2014. 
  7. Chang Y, Tai CL, Hsieh PH, Ueng SW “Gentamicin in bone cement: A potentially more effective prophylactic measure of infectionin joint arthroplasty” Bone Joint Res, 2(10):220-226, Oct. 2013.
  8. Wu MH1, Wang HY1, Tai CL1, Chang YH1, Chen YM, Huang SB, Chiu TK, Yang TC, Wang SS “Development of perfusion-based microbioreactor platform capable of providing tunable dynamic compressive loading to 3-D cell culture construct- Demonstration study of the effect of compressive stimulations on articular chondrocyte functions” Sensor Actuat B-Chem 176:86-96, Jan., 2013.  (1 Equal Contribution)
  9. Lai PL, Tai CL*, Chu IM, Fu TS, Chen LH, Chen WJ “Hypothermic manipulation of bone cement can extend the handling time during vertebroplasty” BMC Musculoskelet Disord,  13:198, doi:10.1186/1471-2474-13-198, Oct., 2012.  (Corresponding Author)
  10. Wu CC, Tai CL “Retrograde nailing of a femoral supracondyle” Orthopedics, 35(4):e491-6. doi: 10.3928/01477447-20120327-20, Apr., 2012.
  11. Tai CL, Tsai SL, Chang YH, Hsieh PH “Study the effect of polymerization temperature in the release of antibiotic from bone” Bio-Med Mater Eng, 21(5-6):341-346, 2012.
  12. Lai PL, Tai CL*, Chen LH, Nien NY “Cement leakage causes potential thermal injury in vertebroplasty” BMC Musculoskelet Disord, 12:116, doi:10.1186/1471-2474-12-116, 2011.  (Corresponding Author)
  13. Chen LH, Tai CL*, Lee DM, Lai PL, Lee YC, Niu CC, Chen WJ “Pullout strength of pedicle screws with cement augmentation in severe osteoporosis: A comparative study between cannulated screws with cement injection and solid screws with cement pre-filling” BMC Musculoskelet Disord, 12:33, doi:10.1186/1471-2474-12-33, 2011. (Corresponding Author)
  14. Tai CL, Lin CL, Wang HW, Lee DM, Hsieh PH “Stress distribution of a modified periacetabular osteotomy for treatment of dysplastic acetabulum” J Med Biol Eng, 31(1):53-58, 2011.
  15. Ueng SW, Lee MS, Tai CL, Hsu KY, Lin SS, Chan YS, Chen WJ “Hyperbaric oxygen therapy improves medial collateral ligament healing in a rabbit model” Formosa J Musculoskelet Disord, 2:7-11, 2011.
  16. Tai CL, Lee DM, Hsieh PH “The influence of surface roughness and cementing technique on the microstructure and mechanical strength at the cement-prosthesis interface” Biomed Eng-App Bas C, Oct; 22(5):419-26, 2010.
  17. Wu CC, Tai CL “Effect of lag-screw positions on modes of fixation failure in elderly patients with unstable intertrochanteric fractures of the femur.” J Orthop Surg (Hong Kong), 18(2):158-65, 2010.
  18. Chang SCN, Chung HY, Tai CL, Chen KT, Lin TM, Jeng LB “Repair of large scale cranium bone defects by hBMP-2 expressing bone marrow stromal cells: comparison between alginate and collagen type I systems” J Biomed Mater Res A, 94(2):433-41, 2010.
  19. Lin CY, Chang YH, Lin KJ, Yen TC, Tai CL, Chen CY, Lo WH, Hsiao IT, Hu YC “The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells” Biomaterials, 31(12):3222-3230, 2010.  
  20. Huang TW, Huang KC, Lee PC, Tai CL, Hsieh PH. “Encouraging Outcomes of Staged, Uncemented Arthroplasty With Short-Term Antibiotic Therapy for Treatment of Recalcitrant Septic Arthritis of the Native Hip” J Trauma, 68(4):965-9, 2010.  
  21. Tai CL, Chen WP, Chen SH, Lin CY, Lee MS “Biomechanical optimization of different fixation modes for a proximal femoral L-osteotomy” BMC Musculoskelet Disord, 10:112, doi:10.1186/1471-2474-10-112, 2009.  
  22. Wu CC, Tai CL “Reconstruction interlocking nails for ipsilateral femoral neck and shaft fractures: biomechanical analysis of effect of supplementary cannulated screw on intracapsular femoral neck fracture” Clin Biomech, 24(8):642-7, 2009.  
  23. Chen LH, Tai CL, Lai PL, Lee DM, Tsai TT, Fu TS, Niu CC, Chen WJ “Pullout strength for cannulated pedicle screws with bone cement augmentation in severely osteoporotic bone: Influences of radial hole and pilot hole tapping” Clin Biomech, 24(8):613-8, 2009.
  24. Chang SCN, Tai CL, Chung HY, Lin TM, Jeng LB “Bone marrow mesenchymal stem cells form ectopic woven bone in vivo through endochondral bone formation.” Artif Organs, 33(4):301-8. 2009.
  25. Hsieh PH, Huang KC, Tai CL “Liquid gentamicin in bone cement spacers: in vivo antibiotic release and systemic safety in two-stage revision of infected hip arthroplasty.” J Trauma, 66(3):804-8, 2009.
  26. Hsieh PH, Tai CL*, Lee PC, Chang YH “Liquid Gentamicin and Vancomycin in Bone Cement- A Potentially More Cost-Effective Regimen” J Arthrop, 24(1):125-30, 2009. (Corresponding Author)
  27. Tai CL, Hsieh PH, Chen WP, Chen LH, Chen WJ, Lai PL “Biomechanical comparison of lumbar spine instability between laminectomy and bilateral laminotomy for spinal stenosis syndrome- an experimental study in porcine model” BMC Musculoskelet Disord. 9(1):84, doi:10.1186/1471-2474-9-84, 2008.
  28. Hsieh PH, Tai CL, Liaw JW, Chang YH “Thermal damage potential during hip resurfacing in osteonecrosis of the femoral head” J Orthop Res, 26(9):1206-1209, 2008.   
  29. Chen SH, Tai CL, Lin CY, Chen WP “Biomechanical comparison of a new stand-alone anterior lumbar interbody fusion cage with established fixation techniques- a three-dimensional finite element analysis” BMC Musculoskelet Disord, 9(1):88, doi:10.1186/1471-2474-9-88, 2008.
  30. Tai CL, Lee MS, Lian LL, Chen WP “The biomechanical study of a modified intertrochanteric valgus osteotomy- A three-dimensional finite element analysis” Chin J Orthop Trauma; 9(6):510-14, 2007.
  31. Lee MS, Chen CY, Kuo CH, Tai CL, Vinesh Senan, Shih CH “The position of the bipolar cup reflects the direction of the hip contact force acting on it” J Arthroplasty, 22(2):189-94, 2007.
  32. Wu CC, Tai CL “Plating treatment for tibial plateau fractures: a biomechanical comparison of buttress and tension band positions” Arch Orthop Trauma Surg, 127:19-24, 2007.
  33. Hsieh PH, Tai CL, Chang YH, Lee MS, Shih HN, Shih CH “Pre-cooling of the femoral canal enhances the shear strength at the cement-prosthesis interface and reduces the polymerization temperature” J Orthop Res, 24(9):1809-14, 2006.
  34. Chen LH, Lai PL, Tai CL, Niu CC, Fu TS, Chen WJ “The effect of supraspinous ligament integrity on adjacent instability after lumbar instrumentation and laminectomy– An experimental study in porcine model” Bio-Med Mater Eng, 16(4):261-267, 2006.  
  35. Lee MS, Tai CL, Vinesh Senan, Shih CH, Lo SW, Chen WP “The effect of necrotic lesion size and rotational degree on the stress reduction in transtrochanteric rotational osteotomy for femoral head osteonecrosis-A three-dimensional finite element simulation” Clin Biomech, 21(9): 969-76, 2006.
  36. Wu CC, Tai CL “A biomechanical comparison of unlocked or locked reamed intramedullary nails in the treatment of mid-third simple transverse femoral shaft fractures” Chang Gung Med J, 29:275-82, 2006.
  37. Wang IC, Ueng SW, Yuan LJ, Tu YK, Wang CR, Lin SS, Tai CL, Wang KC “Early administration of hyperbaric oxygen therapy in distraction osteogenesis- a quantitative study in New Zealand rabbits” J Trauma, 58(6):1230-1235, 2005.
  38. Tai CL, Lee MS, Chen WP, Hsieh PH, Lee PC, Shih CH “Biomechanical comparison of newly designed stemless prosthesis and the conventional hip prosthesis- an experimental study” Bio-Med Mater Eng, 15(3):239-249, 2005.
  39. Chen WP, Tai CL, Tan TF, Shih CH, Hou SH, Chen CY, Lee MS “The degree to which transtrochanteric rotational osteotomy in osteonecrosis of the femoral head moves the region of necrosis out of the weight bearing area as evaluated by computer simulation” Clin Biomech, 20(1):63-69, 2005. 
  40. Tai CL,, Chen WP, Lee MS, Lee PC, Shih CH “Comparison of stress shielding between straight and curved stems in cementless total hip arthroplasty – an in vitro experimental study” J Med Biol Eng, 24(4):177-181, Dec, 2004.
  41. Chen WP, Tai CL, Lee MS, Lee PC, Shih CH “Comparison of stress shielding among different cement fixation modes of femoral stem in total hip arthroplasty- a three-dimensional finite element analysis” J Med Biol Eng, 24(4):183-187, Dec, 2004.
  42. Hsu RWW, Hsu WH, Tai CL, Lee KF “Effect of hyperbaric oxygen therapy on patellar tendinopathy in a rabbit model” J Trauma, 57(5):1060-1064, 2004.
  43. Chen WJ, Lai PL, Tai CL, Chen LH, Niu CC “The effect of sagittal alignment on adjacent instability after lumbar instrumentation– a biomechanical study of lumbar vertebrae in the porcine model” Clin Biomech, 19(8):763-768, 2004.
  44. Chen WP, Tai CL, Shih CH, Hsieh PH, Leou MC, Lee Mel S “Selection of fixation devices in proximal femur rotational osteotomy- a report of clinical complications and finite element analysis” Clin Biomech, 19(3):255-262, 2004.
  45. Lee PC, Yu SW, Hsieh PH, Chuang TY, Tai CL, Shih CH “Treatment of early cut-out of a lag screw using a trochanter supporting plate: 11 consecutive patients with unstable intertrochanteric fractures” Arch Orthop Trauma Surg, 124(2):119-122, 2004.
  46. Hsu RWW, Hsu WH, Tai CL, Lee KF “Effect of shock wave therapy on patellar tendinopathy in a rabbit model” J Orthop Res, 22:221-227, 2004.
  47. Chang SCN, Wei FC, Chuang H, Chen YR, Chen JK, Lee KC, Chen PKT, Tai CL, Lou J “Ex vivo gene therapy in autologous critical size craniofacial bone regeneration” Plast Reconstr Surg, 112(7):1841-50, 2003.
  48. Chang SCN, Chuang HL, Chen YR, Chen JK, Chung HY, Liu YL, Lin HY, Tai CL, Lou J. “Ex vivo gene therapy in autologous bone marrow stromal stem cells for tissue-engineered maxillofacial bone regeneration” Gene ther, 10:2013-2019, 2003.
  49. Tai CL, Shih CH, Chen WP, Lee Mel S, Liu YL, Hsieh PH, Chen WJ “Finite element analysis of the Cervico-Trochanteric stemless prosthesis” Clin Biomech, 18 (6):S53-S58, 2003.
  50. Hsu RWW, Tai CL, Chen CYC, Hsu WH “Enhances mechanical strength during early fracture healing via shockwave treatment: an animal study. Clin Biomech, 18(6):S33-S39, 2003.
  51. Huang TJ, Hsu RWW, Tai CL, Chen WP “A biomechanical analysis of triangulation of anterior vertebral double-screw fixation” Clin Biomech, 18 (6):S40-S45, 2003.
  52. Chen WJ, Lai PL, Chang CH, Lee Mel S, Chen CH, Tai CL “The effect of hyperbaric oxygen therapy on spinal fusion: using the model of posterolateral intertransverse fusion in rabbits” J Trauma, 52(2):333-338, 2002.
  53. Wu CC, Shih CH, Chen WJ, Tai CL “Tension-band technique for ankle fusion” Orthopedics, 24(1):37-40, 2001.
  54. Wu CC, Tai CL, Chen, WJ “Patellar tension band wiring: a revised technique” Arch Orthop Trauma Surg, 121, 12-16, 2001.
  55. Wu CC, Tai CL, Shih, CH “Biomechanical comparison for different configurations of tension band wiring techniques in treating an olecranon fracture” J Trauma, 48(6):1063-1067, 2000.
  56. Lee PC, Shih CH, Yen WL, Yang WE, Tu YK, Tai CL “Complications of liner locking system in Micro-structured Omnifit acetabular components: a radiographic evaluation of 887 hips followed for 5-10 years” Acta Orthop, 71(1):31-33, 2000.
  57. Lee PC, Shih CH, Yu SW, Yen WL, Su JY, Tai CL “MicroStructured Omnifit acetabular components: concerns with locking system complications and excessive polyethylene wear” Chang Gung Med J, 23:156-163, 2000.
  58. Lee PC, Shih CH, Chen WJ, Tu YK, Tai CL “Early polyethylene wear and osteolysis in cementless total hip arthroplasty-the influence of femoral head size and polyethylene thickness” J Arthroplasty, 14(8):976-981, 1999.
  59. Ueng SW, Lee Mel S, Lin SS, Wang CR, Liu SJ, Tai CL, Shih CH “Hyperbaric oxygen therapy mitigates the adverse effect of cigarette smoking on the bone healing of tibia lengthening: An experimental study on rabbits” J Trauma, 47(4):752-759, 1999.
  60. Wu CC, Shih CH, Chen WJ, Tai CL “Treatment of ununited femoral shaft fractures associated with locked nail breakage: comparison between closed and open revision technique” J Orthop Trauma, 13(7):494-500, 1999.
  61. Wu CC, Shih CH, Chen WJ, Tai CL “Effect of reaming bone grafting on treating femoral shaft aseptic nonunion after plating” Arch Orthop Trauma Surg, 119(5/6):303-307, 1999.
  62. Wu CC, Shih CH, Chen WJ, Tai CL “Treatment of femoral neck nonunions with a sliding compression screw: comparison with and without subtrochanteric valgus osteotomy” J Trauma, 46(2):312-317, 1999.
  63. Ueng SW, Lin SS, Wang CR, Liu SJ, Tai CL, Shih CH “Bone healing of tibial lengthening is delayed by cigarette smoking: study of bone mineral density and torsional strength on rabbits” J Trauma, 46(1):110-115, 1999.
  64. Wu CC, Shih CH, Chen WJ, Tai CL “High success rate with exchange nailing to treat a tibial shaft aseptic nonunion” J Orthop Trauma, 13(1):33-38, 1999.
  65. Wu CC, Shih CH, Chen WJ, Tai CL “Treatment of clavicular aseptic nonunion: comparison of plating and intramedullary nailing techniques” J Trauma, 45(3):1-5, 1998.
  66. Wu CC, Shih CH, Chen WJ, Tai CL “Staple augmentation to treat a humeral nonunion after failed seidel locked nailing” Arch Orthop Trauma Surg, 118:42-44, 1998.
  67. Yang WE, Shih CH, Tai CL, Lin SS, Shih IJ “Biomechanical properties of bone ingrowth cement” J Orthop Surg, 15:83-88, 1998.
  68. Ueng SW, Lee Mel S, Lin SS, Wang CR, Liu SJ, Tai CL, Shih CH “Bone healing of tibia lengthening is enhanced by hyperbaric oxygen therapy: A study of bone mineral density and torsional strength on rabbits” J Trauma, 44(4):676-681, 1998.
  69. Wu CC, Shih CH, Chen WJ, Tai CL, “Treatment of cutout of a lag screw of a dynamic hip screw in an intertrochanteric fracture” Arch Orthop Trauma Surg, 117:193-196, 1998.
  70. Shih CH, Chen WP, Tai CL, Kuo RF, Wu CC, Chen CH “New concept- biomechanical studies of newly designed femoral prosthesis (cervical - trochanter prosthesis)” Clin Biomech, 12(7):482-490, 1997.
  71. Shih CH, Lee PC, Chen JH, Tai CL, Chen LF, Wu SS, Chang Walter H “Measurement of polyethylene wear in cementless total hip arthroplasty” J Bone Joint Surg Br, 79(3):361-365, 1997.
  72. Tai CL, Shih CH “Mechanical testing of polymethyl methacrylate bone cement impregnated with bone and hydroxyapatite” J Med Biol Eng, 17(1):1-8, 1997.
  73. Ueng SW, Lee MY, Li FY, Tai CL, Shih CH “Effect of intermittent cigarette smoke inhalation on tibia lengthening: experimental study on rabbits” J Trauma, 42(2):231-238, 1997. 
  74. Wu CC, Shih CH, Chen WJ, Tai CL “Quiescent infected nonunion of a tibia treated by intramedullary reaming with external fixation” J Orthop Surg, 5(2):57-64, 1997.
  75. Chen WP, Yen CG, Shih CH, Tai CL “Automatic finite element mesh generation of proximal femur and prosthesis” J Med Biol Eng, 17(4):231-240, 1997.  
  76. Wu CC, Shih CH, Lee MY, Tai CL “Biomechanical analysis of location of lag screw of a dynamic hip screw in treatment of unstable intertrochanteric fracture” J Trauma, 41(4):699-702, 1996.