Dr.Kin Fong Lei _ Associate Professor

  Ph.D., The Chinese University of Hong Kong
Field:Microfluidics; Bio-sensing; MEMS
Research Topics:Electrical immunoassay chip; Manipulation of bio-molecules; Microfluidic diagnostic devices; Investigation of microfluidic mixing
TEL:03-2118800 ext 5345
LAB:Bio-MEMS LaboratoryTEL:


l          Ph.D., Automation and Computer-Aided Engineering, The Chinese University of Hong Kong, Hong Kong
l          M.Phil., Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong
l          B.Eng., National Tsing Hua University, Taiwan


Research of Interest

Bio-MEMS, Microfluidics, Manipulation of Bio-molecules, Bio-sensing


Selected Publication 

1.          Kin Fong Lei*, Chia-Hao Huang, “Paper-based Microreactor Integrating Cell Culture and Subsequent Immunoassay for the Investigation of Cellular Phosphorylation”, ACS Applied Materials & Interfaces, 6:22423-22429, 2014.

2.          Kin Fong Lei*, Shih-I Yang, Shiao-Wen Tsai, Hsiao-Ting Hsu, “Paper-based Microfluidic Sensing Device for Label-free Immunoassay Demonstrated by Biotin-Avidin Binding Interaction”, Talanta, 134:264-270, 2015..

3.          Kin Fong Lei*, I-Chi Lee*, Yung-Chiang Liu, Yu-Chieh Wu, “Successful Differentiation of Neural Stem/Progenitor Cells Cultured on Electrically Adjustable Indium Tin Oxide (ITO) Surface”, Langmuir, 30:14241-14249, 2014.

4.          Cihun-Siyong Alex Gong, Kin Fong Lei*, Yih-Shiou Hwang, Jia-Hua Zhang, Tim C. Lei, “Impedimetric Detection of Whole Blood Concentration for Early Detection of Intraocular Hemorrhage”, Microelectronic Engineering, 129:70-76, 2014.

5.          Kin Fong Lei*, Kuan-Hao Chen, Yu-Chen Chang, "Protein Binding Reaction Enhanced by Bi-directional Flow Driven by on-chip Thermopneumatic Actuator", Biomedical Microdevices, 16:325-332, 2014.

6.          Yen-Heng Lin*, Chia-Chu Wang, Kin Fong Lei, "Bubble-driven Mixer Integrated with a Microfluidic Bead-based ELISA for Rapid Bladder Cancer Biomarker Detection", Biomedical Microdevices, 16:199-207, 2014.

7.          Kin Fong Lei*, Kun-Fei Lee, Ming-Yih Lee, "A Flexible PDMS Capacitive Tactile Sensor with Adjustable Measurement Range for Plantar Pressure Measurement", Microsystem Technologies, 20:1351-1358, 2014.

8.          Cihun-Siyong Alex Gong, Kin Fong Lei*, “Advances in Miniaturized Instruments for Genomics”, BioMed Research International, 2014:734675, 2014.

9.          Kin Fong Lei*, "Review on Impedance Detection of Cellular Responses in Micro/Nano Environment", Micromechines, 5:1-12, 2014.

10.      Kin Fong Lei*, Min-Hsien Wu, Che-Wei Hsu, Yi-Dao Chen, "Real-time and Non-invasive Impedimetric Monitoring of Cell Proliferation and Chemosensitivity in a Perfusion 3D Cell Culture Microfluidic Chip", Biosensors and Bioelectronics, 51:16-21, 2014.

11.      Kin Fong Lei*, Kuan-Hao Chen, Po-Hsiang Tsui, Ngan-Ming Tsang, "Real-time Electrical Impedimetric Monitoring of Blood Coagulation Process under Temperature and Hematocrit Variations Conducted in a Microfluidic Chip", PLoS ONE, 8:e76243, 2013.

12.      Kin Fong Lei*, Shih-I Yang, "Bundled Carbon Nanotube-based Sensor on Paper-based Microfluidic Device", Journal of Nanoscience and Nanotechnology, 13:6917-6923, 2013.

13.      Kin Fong Lei*, Shin-Chung Cheng, Ming-Yih Lee, Wen-Yen Lin, "Measurement and Estimation of Muscle Contraction Strength using Mechanomyography based on Artificial Network Algorithm", Biomedical Engineering: Applications, Basis and Communications, 25:1350020, 2013.

14.      Wen-Wei Tsai, Ming-Yih Lee*, Wen-Lin Yeh, Shih-Chung Cheng, Kok-Soon Soon, Kin Fong Lei, Wen-Yen Lin, "A Quantitative Method for Evaluating Inferior Glenohumeral Joint Stiffness using Ultrasonography", Medical Engineering & Physics, 35:236-240, 2013.

15.      Kin Fong Lei*, "Recent Developments and Patents on Biological Sensing using Nanoparticles in Microfluidic Systems", Recent Patents on Nanotechnology, 7:81-90, 2013.

16.      Kin Fong Lei*, Min-Hsien Wu, Che-Wei Hsu, Yi-Dao Chen, "Electrical Impedance Determination of Cancer Cell Viability in a 3-Dimensional Cell Culture Microfluidic Chip", International Journal of Electrochemical Science, 7:12817-12828, 2012.

17.      Kin Fong Lei*, Min-Hsien Wu, Che-Wei Hsu, Cheng-Yuan Lin, "Quantification of Cell Number in 3-Dimensional Cell Culture Construct by Impedance Measurement using Microfluidic Technology", International Journal of Electrochemical Science, 7:8848-8858, 2012.

18.      Kin Fong Lei*, Kun-Fei Lee, Shih-I Yang, "Fabrication of Carbon Nanotube-based pH Sensor for Paper-based Microfluidics", Microelectronic Engineering, 100:1-5, 2012.

19.      Kin Fong Lei*, Kun-Fei Lee, Ming-Yih Lee, "Development of a Flexible PDMS Capacitive Pressure Sensor for Plantar Pressure Measurement", Microelectronic Engineering, 99:1-5, 2012.

20.      Kin Fong Lei*, "Microfluidic Systems for Diagnostic Applications: A Review", Journal of Laboratory Automation, 17:330-347, 2012.

21.      Kin Fong Lei*, Kun-Fei Lee, Cheng-You Li, "Analysis of the Flexible PDMS Capacitive Microsensor for the 3-axis Force Measurement", Micro and Nanosystems, 4(3):208-213, 2012.

22.      Kun-Fei Lee, Kin Fong Lei*, "A Review on Tactile Sensors for Biomechanical Applications", Journal of Advanced Engineering, 7(4):151-159, 2012.

23.      Kin Fong Lei*, Min-Hsien Wu, Pei-You Liao, Yan Ming Chen, Tung-Ming Pan, "Development of a Micro-scale Perfusion 3D Cell Culture Biochip with an Incorporated Electrical Impedance Measurement Scheme for the Quantification of Cell Number in a 3D Cell Culture Construct", Microfluidics and Nanofluidics, 12:117-125, 2012.

24.      Kin Fong Lei*, Polly H.M. Leung, "Microelectrode Array Biosensor for the Detection of Legionella pneumophila", Microelectronic Engineering, 91:174-177, 2012.

25.      Kin Fong Lei*, "Quantitative Electrical Detection of Immobilized Protein using Gold Nanoparticles and Gold Enhancement on a Biochip", Measurement Science and Technology, 22:105802, 2011.

26.      Kin Fong Lei*, "Electrical Detection of Sandwich Immunoassay on Indium Tin Oxide Interdigitated Electrodes", Micro & Nano Letters, 6(3):157-160, 2011.

27.      Kin Fong Lei*, King Sau Wong, “Automated Colorimetric Immunoassay Microsystem for Clinical Diagnostics”, Instrumentation Science & Technology, 38(4):295-304, 2010.

28.      Kin Fong Lei*, Yoki K.C. Butt, “Colorimetric Immunoassay Chip based on Gold Nanoparticles and Gold Enhancement”, Microfluidics and Nanofluidics, 8:131-137, 2010.

29.      Kin Fong Lei*, Han Cheng, Kit Ying Choy, Larry M.C. Chow, “Electrokinetic DNA Concentration in Micro Systems”, Sensors and Actuators A: Physical, 156:381-387, 2009.

30.      Han Cheng, Kin Fong Lei*, Kit Ying Choy, Larry M.C. Chow, “Single-stranded DNA Concentration by Electrokinetic Force”, Journal of Micro/Nanolithography, MEMS, and MOEMS, 8:021107, 2009.

31.      Kin Fong Lei*, Wen J. Li, “A Novel In-plane Microfluidic Mixer using Vortex Pumps for Fluidic Discretization”, Journal of Laboratory Automation, 13(4):227-236, 2008.

32.      Kin Fong Lei, Wing Cheung Law, Yick-Keung Suen, Wen J Li*, Yeung Yam, Ho Pui Ho, Siu-Kai Kong, "A Vortex-Pump Based Optically-Transparent Microfluidic Platform for Biotech and Medical Applications”, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 221(2):129-141, 2007.

33.      Winnie W. Y. Chow, Kin Fong Lei, Guangyi Shi, Wen J. Li*, Qiang Huang, “Microfluidic Channel Fabrication by PDMS-Interface Bonding”, Smart Material and Structure, 15(1):s112-s116, 2006.

34.      Kin Fong Lei, Wen J. Li*, Yeung Yam, "Effects of Contact-Stress on Hot-Embossed PMMA Microchannel Wall Profile", Microsystem Technologies, 11(4-5):353-357, 2005.

35.      Kin Fong Lei, Syed Ahsan, Nasser Budraa, Wen J. Li*, John D. Mai, “Microwave Bonding of Polymer-Based Substrates for Potential Encapsulated Micro/Nano Fluidic Device Fabrication”, Sensors and Actuators A: Physical, 114(2-3):340-346, 2004.

36.      Kin Fong Lei, Péter Baranyi, Yeung Yam*, “Complexity Minimalisation of Non-singleton Based Fuzzy-Neural Network”, International Journal of Advanced Computational Intelligence, 4(4):1-8, 2000.

Fulltime Employment





Current: Chang Gung University

Graduate Institute of Medical Mechatronics

Associate Professor

2014 / 08 to present

Past experience:

Chang Gung University

Graduate Institute of Medical Mechatronics

Assistant Professor

2010 / 09 to 2014 / 07

Hong Kong Polytechnic University

Research Institute of Innovative Products and Technologies


2007 / 10 to 2010 / 06

Hong Kong Productivity Council

Materials Technology Devision

Associate Consultant

2006 / 10 to 2007 / 09

University of Western Ontario, Canada

Surface Science Western

Postdoctoral Fellow

2006 / 03 to 2006 / 09


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